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Innate Pharma's IPH6501 Shows Potential in Lymphoma Treatment

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Innate Pharma presented promising preclinical data for IPH6501 at the 2025 European Hematology Association Congress. IPH6501, an ANKET® targeting CD20, has demonstrated significant antitumor activity in vitro against Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma (FL) patient samples. Furthermore, in vivo models indicate enhanced efficacy when combined with R-CHOP, the current standard care for these lymphomas.

The current Phase 1/2 study investigates IPH6501's potential in relapsed or refractory B-cell non-Hodgkin lymphoma. Early results suggest its capability to improve outcomes in rituximab-resistant scenarios and offer new treatment avenues. This underscores the therapeutic promise of IPH6501 in enhancing existing lymphoma therapies.

R. E.

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