BRIEF

on The Vanguard Group, Inc. (isin : US12572Q1058)

Vanguard Group Discloses Position in Mural Oncology

The Vanguard Group, Inc. has recently released a disclosure under Rule 8.3 of the Irish Takeover Panel Act, 1997. This disclosure pertains to Mural Oncology plc, highlighting Vanguard's interests and short positions in the company’s securities. The disclosure was made with respect to ordinary shares valued at $0.01 each.

As of October 28, 2025, Vanguard holds 288,859 shares, constituting approximately 1.67% of Mural Oncology's ordinary shares. The document confirms no other securities interests or short positions, and no cash-settled or stock-settled derivatives are involved.

The disclosure also notes the purchase of 32 additional securities at a unit price of $2.09. No agreements related to voting rights or future acquisitions were recorded. Furthermore, no indemnity arrangements or options have been made.

R. H.

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